About the Academy

A collaborative research training environment

The Ovarian Cancer Academy is a virtual career development and research training platform that consists of Early-Career Investigator/Designated Mentor pairs and two Academy Deans.

Location of Early Career Investigators (2019-2023)

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OCRP Info Booklet

Academy Highlights

BRCA1 GENE FOUND TO HAVE NEW CRITICAL ROLES IN DNA REPAIR

Neil Johnson, PhD finds thab BRCA1 alleles can have separation-of-function mutations that combine to provide a level of HR sufficient for normal development and hematopoiesis. Because BRCA1 activities can be genetically separated, compound heterozygosity may protect individuals from Fanconi anemia.

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Recent Publications

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Jan 27, 2023
Epigenetically programmed resistance to chemo- and immuno-therapies.
Walker RR, Rentia Z, Chiappinelli KB. Adv Cancer Res. Jan 27 2023;158:41-71. doi:10.1016/bs.acr.2022.12.001.
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Dec 7, 2022
PP4 inhibition sensitizes ovarian cancer to NK cell-mediated cytotoxicity via STAT1 activation and inflammatory signaling.
Raja, R., Wu, C. L., Rubino, T. E., Utagawa, E., Magtibay, P. M., Butler, K. A., & Curtis, M. Journ. Immunotherapy of Cancer vol 19, no 12. 2022 Dec 1; e005026 DOI: 10.1136/jitc-2022-005026
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Nov 7, 2022
Inhibiting DNA methylation and RNA editing upregulates immunogenic RNA to transform the tumor microenvironment and prolong survival in ovarian cancer
Gomez, S., Cox, O. L., Walker, R. R., 3rd, Rentia, U., Hadley, M., Arthofer, E., Diab, N., Grundy, E. E., Kanholm, T., McDonald, J. I., Kobyra, J., Palmer, E., Noonepalle, S., Villagra, A., Leitenberg, D., Bollard, C. M., Saunthararajah, Y., & Chiappinelli, K. B. J Immunother cancer vol. 10,11 Nov 7 2022; e004974. doi:10.1136/jitc-2022-004974.
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